Figure 4: Representative lesions observed in the lungs of three specimens of Didelphis virginiana with isolated of Mycobacterium avium subsp. hominissuis (Stain method: H-E). A. Grade Π subpleural granuloma. 100 X. Note the fibrosis of the adjacent lung tissue (arrows) and atelectasis (*). B. Grade Π granuloma associated with the wall of a bronchus and adjacent alveolar tissue. 100 X.