Figure 4: Histopathology of the liver. (A) The control group shows normal histological appearance with the presence of the central vein (CV), nucleus (N), and sinusoidal space (SS); (B) The CCl4-treated group exhibits severe damage with dilated sinusoidal and infiltration of inflammatory cells (1); (C) The group administrered with silymarin showed rounded nucleus with little hydropic degeneration (2); (D and E) Groups administered with methanol extract of rhizome of Curcuma angustifolia at a concentration of 200 mg/kg b.w. and 400 mg/kg b.w. show the presence of the central vein, rounded nucleus, bile duct (BD), portal vein (PV) and scant hydropic degeneration. (Magnification 10X).