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Figure 2: Expression of PBP2a-related genes. PCR showing the expression of mecA, mecI, and mecR1 of MRSA exposed to various concentrations of rhein alone or in combination with 31.25 μg/mL oxacillin. 16s rRNA was used as a loading control, and expression levels were normalized to 16s rRNA levels. Different letters (a-e) indicate significant differences at P<0.05 based on analysis of variance followed by the Scheffe's test for multiple comparisons. Values are presented as mean±SD. |
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