Figure 5: Prediction of structural protein position. [A] Structural superposition between the homology model of the MAYV NSP3 macrodomain (light cyan cartoon 0 and the template macrodomain from Venezuelan Equine Encephalitis virus [orange]. The ligand ADP-ribose is depicted by yellow sticks. Arrow indicates the position 31 occupied by an Asp residue. [B] Surface of the MAYV macrodomain colored according to the protein-protein interaction potential using a scale ranging from blu (low potential) to red (high potential). Arrow marks the position 31. ADP-ribose is displayed as in panel A.