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CASE REPORT
Year : 2022  |  Volume : 15  |  Issue : 7  |  Page : 332-334

A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report


1 Department of Neurology, Renai Medicity Multi Super Speciality Hospital, Kochi, Kerala, India
2 Department of Nephrology, Renai Medicity Multi Super Speciality Hospital, Kochi, Kerala, India
3 Department of General Medicine, Renai Medicity Multi Super Speciality Hospital, Kochi, Kerala, India

Correspondence Address:
Minu George
Department of Neurology, Renai Medicity Multi Super Speciality Hospital, Kochi, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1995-7645.351765

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Rationale: To report a case of cervicobrachial variant of acute inflammatory demyelinating polyneuropathy presenting with papilledema and GQ1b positivity. Patient concern: A 35-year-old female, 68 days postpartum, presented with headache, vomiting, and gait difficulty in swallowing with bilateral upper limb weakness and difficulty in walking, 13 days after ChAdOx1 nCoV-19 vaccination. Diagnosis: Guillain-Barre syndrome with GQ1b positivity. Intervention: Five cycles of plasmapheresis were given. Outcome: The patient’s clinical condition improved. Palatal weakness improved and she could walk without support. There were mild sensory symptoms involving upper limbs which gradually improved. Lessons: AIDP should be considered in case of weakness following ChAdOx1 nCoV-19 vaccination. Albumino-cytological dissociation and anti-GQ1b positivity are needed to confirmed the diagnosis.


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