CASE REPORT |
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Year : 2022 | Volume
: 15
| Issue : 10 | Page : 474-476 |
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Neurological paradox during treatment in a non-HIV patient with pulmonary tuberculosis: A case report
Thanyalak Amornpojnimman, Song Srisilpa, Pornchai Sathirapanya
Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand
Correspondence Address:
Pornchai Sathirapanya Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110 Thailand
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/1995-7645.356995
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Rationale: To report neurological paradox in a non-HIV patient with pulmonary tuberculosis.
Patient concerns: A 26-year-old non-human immunodeficiency virus immunosuppressed female patient presented with diffused headache, diplopia, ascending paraparesis with loss of bowel and bladder control.
Diagnosis: Disseminated neurological paradoxical reaction developed during tuberculosis treatment in a non-human immunodeficiency virus patient.
Intervention: High-dose intravenous corticosteroid was added to the anti-tuberculous drugs, followed by tapered dose of oral prednisolone in 3 months.
Outcome: A favorable neurological outcome was obtained 6 months later.
Lessons: Neurological paradoxical reaction cannot be overlooked among the tuberculosis-treated cases who present with newly emerged neurological disorders.
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