Optimized combinations of statins and azoles against Acanthamoeba trophozoites and cysts in vitro

Ines Sifaoui¹, Carmen M Martín-Navarro², Atteneri López-Arencibia², María Reyes-Batlle², Basilio Valladares², José E Piñero², Sutherland K Maciver³, Jacob Lorenzo-Morales^2
1 University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Canary Islands, Spain; Laboratoire Matériaux-Molécules et Applications, IPEST, LA Marsa, University of Carthage, Tunisia
² University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Canary Islands, Spain
³ Centre for Integrative Physiology, Biomedical Sciences, Edinburgh Medical School, University of Edinburgh, Scotland, UK

Correspondence Address:
José E Piñero
University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Canary Islands
Spain

Source of Support: This work was supported by the grants Red de Investigation Colaborativa en Enfermedades Tropicales RICET (project no. RD16/0027/0001 of the programme of Redes Temáticas de Investigación Cooperativa, FIS), Spanish Ministry of Health, Madrid, Spain and PI13/00490 “Protozoosis Emergentes por Amebas de Vida Libre: Aislamiento, Caracterización, Nuevas Aproximaciones Terapéuticas y Traslación Clínica de los Resultados” from the Instituto de Salud Carlos III. IS and ALA were supported by the Agustín de Betancourt Programme. JEP was supported by Ayudas Plan Propio de la Universidad de La Laguna 2018 (proyectos puente I+D+i), Conflict of Interest: None

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DOI: 10.4103/1995-7645.261287