| REVIEW ARTICLE |
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| Year : 2019 | Volume
: 12
| Issue : 6 | Page : 243-249 |
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Laboratory diagnosis of schistosomiasis mansoni: Current status and future trends
Amira Taman MSc, PhD , Samar N El-Beshbishi
Department of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt
Correspondence Address:
Amira Taman
Associate professor, Department of Medical Parasitology, Faculty of Medicine, Mansoura University, 2 El-Gomhouria Street, Mansoura
Egypt
 Source of Support: None, Conflict of Interest: None  | 5 |
DOI: 10.4103/1995-7645.261270
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Schistosomiasis is a neglected tropical disease that affects about 290 million patients worldwide. Children aged between 5 and 14 years represent 45.8% of the affected patients, in addition, schistosomiasis has been reported in Schistosoma-free areas, mostly because of tourism and immigration from endemic countries. Intestinal schistosomiasis caused by Schistosoma mansoni is mainly diagnosed via direct stool examination for egg detection. Immunological methods are favoured for disease monitoring and preliminary checking for communities in areas with low infection rates, and for patients with light and chronic infections where parasitological tests are negative. PCR-based diagnostic techniques are more sensitive, but expensive. Tegument proteins and miRNAs are promising markers for diagnosis of schistosomiasis. Here we review the diagnostic methods for schistosomiasis mansoni aiming to reach a standardized technique for diagnosis of early infection to help better control of the disease. |
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