Impact Factor 2021: 3.041 (@Clarivate Analytics)
5-Year Impact Factor: 2.776 (@Clarivate Analytics)
Impact Factor Rank: 10/24, Q2 (Tropical Medicine)
  • Users Online: 353
  • Print this page
  • Email this page
Year : 2018  |  Volume : 11  |  Issue : 1  |  Page : 53-57

Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka

1 Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, USA
2 Public Health Specialist /Medical Epidemiologist, Office-WHO Manila, Philippines
3 Department of Microbiology, University of Sri Jayawardenapura, Sri Lanka

Correspondence Address:
Hathshya M Munasingha
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 RPHB, Univ. Blvd., Birmingham, Alabama, 35294
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1995-7645.223561

Rights and Permissions

Objective: To determine the seroprevalence of varicella zoster virus (VZV) antibodies among the population residing in the Colombo district of Sri Lanka. Methods: A cross-sectional population-based study was conducted which included 1 258 participants. Blood samples were collected and questionnaires administered to obtain sociodemographic information and history of varicella and/or herpes zoster. Serum samples were assayed for VZV IgG antibodies using a commercial enzyme-linked immunosorbent assay kit. Results: Overall, the seroprevalence was 54.2% (95% CI = 51.5% 57.0%). Children below 1 year of age were seronegative, and only about 20.0% of children between 1 and 10 years of age were seropositive. Seropositivitiy increased with age and by the age of 40 years 74.3% were seropositive. Among women of childbearing age, the overall seroprevalence was about 62.0% (95% CI = 57.7%-66.1%) but was low 37.0% in the 15-19 age group. Conclusion In this population, 45.8% lacked natural immunity against varicella. Of women of childbearing age, 39.9% lacked immunity and in the subgroup of women 15-19 years of age, 63.0% women lacked immunity. In light of the country's success with the control and high coverage of other vaccine preventable diseases and that the vaccine is available in the private sector, the inclusion of varicella vaccine in the national immunization program may be considered.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded400    
    Comments [Add]    
    Cited by others 3    

Recommend this journal